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We are Ego + Spirit (thank goodness) So I have finally come to the end of Elizabeth Gilbert’s wonderful book, “Big Magic: Creative Living Beyond Fear.” Or (though it typically irks me when others say this) maybe … ...
Important role of nucleocytoplasmic transport in amyotrophic lateral sclerosis and frontotemporal dementia Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating adult-onset neurodegenerative disorders. No cure exists for these diseases. Ten percent of ALS patients suffer from a familial form of the disease, while FTD is caused in 40% of patients by a genetic defect. In 2011, the most important genetic cause of ALS and FTD was discovered. The causative mutation was a repetition of a piece of non-coding DNA, a so called tandem repeat, in a gene with an unknown function, named C9orf72. A team of scientists has now discovered that proteins translated from this tandem repeat interfere with the nucleocytoplasmic transport which they found is essential for causing ALS and FTD.
Combination drug targeting opioid system may help relieve treatment-resistant depression A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of serotonin and related monoamine neurotransmitters.
Today I Love The Closed In Feeling Of Snow Today I love the closed in feeling of snow falling so thick and soft that it makes my world tiny. I love that there is nothing to be seen beyond … ...
Issues That Divide the Mad Community As a psychotherapist who works with other Mad individuals, it seems to me that the wider Mad community is not always aware of the diversity that exists within. Many of us who have survived may fail to see the privileges that we have that have … ...
3 Truths for Life With ADHD One of the best things you can do with an ADHD diagnosis is use it as a starting point for reevaluating your life, questioning your assumptions about what life is … ...
7 Things Sigmund Freud “Nailed” About Love & Sex If there is one thing that almost all of my patients speak about in psychoanalytic psychotherapy in one shape or form, it’s LOVE. Am I really lovable? How do I make my … ...
11 Different Ways to Sound Like a Great Lover A new Love Month cartoon! Last week’s cartoon was the first one for Love Month in Psych Central! It included a Vinegar Valentine, and talked about matters of the heart. … ...
ADHD, ALL Or Nothing It’s 7:30 PM on a Thursday night. I’m at a meeting. It’s a group that I enjoy. And we have a project on the go. I won’t bore you with … ...
Best of Our Blogs: February 12, 2016 Our fear isn’t that we show too much of ourselves, it’s that no one will truly know who we are. The fear of disconnection and loneliness can drive many to divulge too much too soon. It can make us desire intimacy before a relationship is ready. … ...
The Valentine’s Vine: Growing Love in Empty Hearts My grandmother is a sly sage (as so many of our grandmothers seem to be). On our most recent wander through her backyard, when I casually commented on her magnolia … ...
Are Holidays Only for the Happy? Does the "Happy" wish associated with holidays leave you feeling excluded? You are not alone.
The Colourful, Melodramatic Manager: Histrionic Disorder Have you ever worked with or for a "drama queen". Why is there doubt about the concept of Histrionic Personality Disorder
Feeling Older Increases Risk of Hospitalization, Study Says Disease, depression could help explain association
Rexulti, moods, and psychosis I am now back on 4mg of Rexulti – the highest normal dose. I feel good. Wish my boyfriend was here for a hug – but my mood seems pretty … ...
How your brain works against your best intentions Researchers use brain scans to show how our brains seek rewards which might help researchers understand addiction.
Narcissists not necessarily satisfied with themselves Narcissists feel superior to others but aren’t necessarily satisfied with themselves. After reviewing the research literature, UvA researcher Eddie Brummelman and his colleagues conclude that narcissism and self-esteem are much more distinct than conventional wisdom has led us to believe. The results of the study were published earlier today in the journal Current Directions in [...]
Study examines why smiles and frowns are contagious Smile! It makes everyone in the room feel better because they, consciously or unconsciously, are smiling with you. Growing evidence shows that an instinct for facial mimicry allows us to empathize with and even experience other people’s feelings. If we can’t mirror another person’s face, it limits our ability to read and properly react to [...]
Are We Wired for Gratitude?   While we know gratitude is likely to make us feel better, it may actually have an evolutionary place. Gratitude appears to be cross-culturally and linguistically universal and has been demonstrated repeatedly … ...
How your brain might be secretly thwarting your New Year’s resolutions The human brain is wired to pay attention to previously pleasing things — a finding that could help explain why it’s hard to break bad habits or stick to New Year’s resolutions. In the new issue of Current Biology, Johns Hopkins University neuroscientists demonstrate for the first time that when people see something associated with [...]