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Eye drops deliver gene therapy for brain disorders Eye drops have been used to deliver the gene for a growth factor called granulocyte colony stimulating factor (G-CSF) in a mouse model of brain ischemia. The treatment led to a significant reduction in brain atrophy, neurological deficits, and death in the mice. The research team also devised a system to monitor the success of the gene delivery using MRI. The combination of simple delivery and non-invasive monitoring has the potential to contribute to improved studies of experimental gene therapy in animal models of stroke, Alzheimer’s dementia, Parkinson’s disorder, and ALS. The system also offers the intriguing possibility that acute brain injury may someday be treated by emergency medical workers through the simple delivery of eye drops carrying a therapeutic gene.
'Inner GPS' study may aid diagnosis of brain diseases A new study sheds light on brain cells in our 'inner GPS,' which may improve understanding of memory loss and wandering behavior in people with Alzheimer's and other neurodegenerative diseases.
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Untreated Mental Illness Leaves Two Dead, One Life Shattered Be bold. Be compassionate.